Acute upper respiratory infection( heat in both superficies and interior) in children
Conditions
Interventions
Treatment Group:Xiao'er Chai Qin Granule +Xiao'er Shuangqing Granule Placebo
Control Group:Xiao'er Shuangqing Granule+ Xiao'er Chai Qin Qingjie Granule Placebo
Sponsors
Dongzhimen Hospital Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
1 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed as acute upper respiratory infection according to western medicine diagnostic criteria; Diagnosed as Tradition Chinese Medicine syndrome with heat in both superficies and interior; 2. Aged 1 to 12 years old; 3. Disease progression within 48 hours and the highest axillary temperature =39 degree C before enrollment; 4. Signed informed consent by legal guardiansor jointly signed by the child (=10 years).
Exclusion criteria
Exclusion criteria: 1. Children with lower respiratory infections, such as bronchitis, bronchiolitis and pneumonia; 2. WBC>1.2 ULN, N>1.0 ULN or CRP>1.5 ULN, possibly have a bacterial infection; 3. Children with a history of epilepsy or hyperpyretic convulsion; 4. Children with severe malnutrition, rickets or combined with severe systemic disease such as cardiocerebral vascular system, endocrine system, Hematologic System, liver or kidney disease, etc.; 5. Children who were allergic to the test drug or its components; 6. Children who were not suitable for the clinical research according to the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time for the main clinical symptoms( fever, dry stool) disappeared ; | — |
Secondary
| Measure | Time frame |
|---|---|
| The rate of the main clinical symptoms( fever, dry stool) disappeared;Time needed for full efervescence;Instant time for defervescence/ duration;Efficacy for TCM syndromes;Single TCM syndromes; | — |
Countries
China
Contacts
Public ContactJunhong Wang
Dongzhimen Hospital Beijing University of Chinese Medicine
Outcome results
None listed