infertility
Conditions
Interventions
GnRH antagonist :GnRH antagonist
MPA :MPA
Sponsors
Shanghai Ninth People's Hospital affiliated Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
Female
Age
25 Years to 42 Years
Inclusion criteria
Inclusion criteria: 1. Women who have a history of infertility =1 year 2. Women aged >22 and <42 years 3. Women with spontaneous menstrual cycles of 21–35 days 4. Women who have at least one of the following indications for IVF or ICSI: tubal factor, male factor, diminished ovarian reserve, endometriosis or unexplained factors 5. Women diagnosed as poor responders according to the Bologna criteria, including at least two of the three following criteria: (1) Advanced age (=40 years) or any other risk factor for poor ovarian response; (2) A previous poor response with no more than three oocytes retrieved using the conventional stimulation protocols c. Abnormal ovarian reserve test results, including bilateral antral follicle counts <7 or serum antiMüllerian hormone <1.1 ng/ml.
Exclusion criteria
Exclusion criteria: 1. Clinically significant systemic diseases, such as renal failure and systemic lupus erythematosus; 2. Premature ovarian insufficiency; 3. Up to five previous unsuccessful IVF attempts; 4. Known Müllerian anomalies; 5. Any contraindications to ovarian stimulation treatments; 6. Unable to comply with the study procedures.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of premature LH surge; | — |
Secondary
| Measure | Time frame |
|---|---|
| number of oocyte retrieved;number of viable embryos; | — |
Countries
China
Contacts
Public ContactKuang Yanping
Shanghai Ninth People's Hospital affiliated Shanghai Jiaotong University School of Medicine
Outcome results
None listed