discogenic low back pain
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. The diagnostic criteria of Park WM for discogenic low back pain(Park WMMcCall IWO'Brien JPet al. Fissuring of the posterior annulus fibrosus in the lumbar spine[J]. Britith Journal of Radiology197952(617)382-387.); 2. Aged 20 to 80 years old, male and female; 3. VAS of back pain ranged from 30 t0 80 scores; 4. Volunteer to participate in the trial, and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. A history of spinal surgery; 2. History of severe spinal trauma; 3. The imaging findings included spinal bone tumor, tuberculosis, osteoporosis and other diseases; 4. Cardiovascular diseases such as cardiovascular and digestive system and other serious diseases; 5. Pregnant and lactating women; 6. Liver and kidney dysfunction; 7. Other autoimmune diseases, allergic diseases and acute and chronic infections; 8. Chronic skin disease or operation area with skin ulcer wound scar; 9. The researchers did not think it would be appropriate to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS pain level;Oswestry dysfunction index; | — |
Secondary
| Measure | Time frame |
|---|---|
| TNF-a;IL-1;IL-6; | — |
Countries
China
Contacts
The First Affiliated Hospital of Sun Yat-sen University University