A study on the effects of different doses of atorvastatin on vulnerable plaque of coronary artery by optical coherence tomography

A serial studies of fiber cap of lipid plaque by optical coherence tomography in patients with acute coronary syndrome

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-17010874

Enrollment

Unknown

Registered

2017-03-15

Start date

2012-06-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute coronary syndrome

Interventions

routine dose:20mg atorvastatin

intensive dose :40-80mg atorvastatin

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-80 years; 2. Acute coronary syndrome(STMEI/NSTEMI/UAP); 3. Tolerance to atorvastatin therapy; 4. Vulnerable plaque without immediate intervention by optical coherence tomography.

Exclusion criteria

Exclusion criteria: 1. Severe hepatic and renal insufficiency; 2. Severe systemic disease; 3. Taking other statins or lipid-lowering drugs.

Design outcomes

Primary

Measure	Time frame
Fibrous cap thickness;	—

Secondary

Measure	Time frame
Lipid core angle;	—

Countries

China

Contacts

Public ContactYe Honghua

Ningbo 1st Hospital

1946886281@qq.com+86 13505743664

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 23, 2026