Chronic Obstructive Pulmonary Disease
Conditions
Interventions
Intervention:sdg
Control:Maintain the original medication
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) aged at 40–80 years old; 2) spirometry confirmed diagnose of COPD with at least one exacerbation before, and stable for at least three months; 3) quit smoking for more than six months; 4) be able to engage in daily activities; 5) have willing to participate in this study, follow the research program and have the ability to sign the informed consent; 6) Beijing residents; 7) can be contacted;
Exclusion criteria
Exclusion criteria: 1) history of asthma, lung cancer, active pulmonary tuberculosis, bronchiectasis, diffuse lung disease (interstitial pneumonia, pulmonary sarcoidosis, occupational lung disease, sarcoidosis et al) and pleural disease; 2) history of lobectomy and / or lung transplantation; 3) predicted life expectancy less than 3 years; 4) history of severe psychiatric illnesses, mental disorders, neurological disorders, malignant tumors, chronic liver disease, heart failure, autoimmune diseases, chronic kidney disease; 5) Never engage in outdoor activities; 6)?? 7) expected to move out of the city in 3 years; 8) Plan to carry out an indoor redecoration during the study; 9) Alcoholism, drug abuse or abuse of toxic solvents; 10) Allergic to the study drug or its ingredients, or have a clear contraindication of it; 11) Participation in another clinical trial; 12) Cannot finish long term follow-up or poor compliance; 13) Do not provide consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| frequency of exacerbation per year; | — |
Secondary
| Measure | Time frame |
|---|---|
| number of unplanned outpatient visits due to exacerbation per year;number of emergency visits due to exacerbation per year;number of hospitalization due to exacerbation per year;cost due to exacerbation per year;Mortality rate associated with COPD exacerbation; | — |
Countries
China
Contacts
Public ContactGuangfa Wang
Peking University First Hospital
Outcome results
None listed