Pediarteric Disease
Conditions
Interventions
control group:normal saline
0.25µg/kg dexmedetomidine group:0.25µg/kg dexmedetomidine rapid infused
0.5µg/kg dexmedetomidine group:0.5µg/kg dexmedetomidine rapid infused
0.75µg/kg dexmedetomidine group:0.75µg/kg dexmedetomidine rapid infused
1µg/kg dexmedetomidine group:1µg/kg dexmedetomidine rapid infused
Sponsors
The second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
4 Years to 10 Years
Inclusion criteria
Inclusion criteria: (1) selective operation of inguinal hernia repair in children; (2) aged 4-10 years; (3) ASA I - II; (4) enter the operating room by himself without parents; (5) normal liver and kidney function; (6) no history of anesthesia medication allergy.
Exclusion criteria
Exclusion criteria: (1) allergic to dexmedetomidine, similar active ingredients or excipients; (2) G-6-PD; (3) a history of arrhythmia, bronchial and cardiovascular diseases, abnormal liver function and so on; (4) a history of use of alpha 2 receptor agonists or antagonists.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| heart rate;plasma concentration;Emergence Agitation; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood pressure;Respiratory frequency;Tidal volume; | — |
Countries
China
Contacts
Public ContactFang Chen
The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University
Outcome results
None listed