Comparison of two kinds of sedations and analgesia solution for heart vascular surgery patients: Dexmedetomidine combined morphine VS propofol combined morphineP

Comparison of two kinds of sedations and analgesia solution for heart vascular surgery patients: Dexmedetomidine combined morphine VS propofol combined morphine

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-17010603

Enrollment

Unknown

Registered

2017-02-09

Start date

2017-02-28

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Disease

Interventions

Dexmedetomidine Group: Dexmedetomidine combined morphine

Propofol group:Propofol combined morphine

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) the age =18 years; (2) undergoing elective cardiovascular surgery; (3) postoperative patients need staying in intensive care unit (ICU) with mechanical ventilation.

Exclusion criteria

Exclusion criteria: 1. acute severe neurological disorder; 2. mean arterial pressure less than 55mmHg; 3. heart rate less than 50/min; 4. atrioventricular-conduction; 5. dexmedetomidine or propofol allergy or other contradications.

Design outcomes

Primary

Measure	Time frame
heart rhythm;respiratory;acute kidney injury;pneumonia;Postoperative length of hospital stay;Length of ICU stay;consolidation of the lung;vasoplegia;	—

Secondary

Measure	Time frame
Delirium;Mechanical ventilation time;	—

Countries

China

Contacts

Public ContactKang Hui

West China Hospital, Sichuan University

kkzaihuaxi@qq.com+86 13881907302

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026