Effects of dexmedetomidine on early postoperative cognitive dysfunction in the elderly

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-17010496

Enrollment

Unknown

Registered

2017-01-22

Start date

2017-01-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative cognitive dysfunction

Interventions

DEX group:Intraoperative injection of dexmedetomidine

NS group:Intraoperative injection of saline

Eligibility

Sex/Gender

All

Age

60 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients aged 60 to 80 years undergoing the sugery of arthroplasty, TUR-P or thoracotomy in shengjing hospital affiliated to china medical university

Exclusion criteria

Exclusion criteria: Patiens who have severe systemic disease, a history of mental illness and treatment, history of surgery and treatment of central nervous system, audio-visual obstacles or communication difficulties and low scores of MMSE will be excluded

Design outcomes

Primary

Measure	Time frame
ISPOCD test-battery score;IL-6;IL-1ß;S100ß protein;	—

Secondary

Measure	Time frame
VAS;Ramsey;	—

Countries

China

Contacts

Public ContactPeng Qiu

Shengjing Hospital affiliated to China Medical University

storm0513@sohu.com+86 18940255857

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026