unstable angina pectoris
Conditions
Interventions
treatment group:Experimental drug: salvianolate
control group:ordinary drug
Sponsors
Chinese General Hospital of PLA
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Patient in line with 1979 WHO diagnostic criteria for UA; 2. Aged 60-85 years; 3. Traditional Chinese medicine for CHD treatment should be stopped at least 1 week;take CHD drugs standardly; 4. Participates give written informed consent.
Exclusion criteria
Exclusion criteria: 1. NSTE-ACS caused by non atherosclerotic disease; 2. Angina pectoris caused by violent activities, fever, tachycardia, high adrenergic state, mental stress, lack of sleep, eating too full, left ventricular load increased (hypertension, aortic stenosis); 3. Angina pectoris caused byanemia, methemoglobinemia and hypoxemia; 4. Abnormal thyroid function; 5. Poorly controlled hypertension (systolic pressure =160mmHg or diastolic blood pressure =100mmHg); 6. Severe cardiopulmonary dysfunction; 7. Severe arrhythmia (atrial fibrillation, atrial flutter, paroxysmal ventricular tachycardia, sinus bradycardia (heart rate < 55), complete left bundle branch block; 8. Combined liver and kidney and hematopoietic system and other serious diseases, liver function (ALT, AST) 3 times higher than the upper limit of normal renal function, creatinine clearance rate (CrCl) less than 30 ml/min/1.73m2; 9. Recent 4 weeks underwent surgery and bleeding tendency; 10. Poor compliance; 11. At the same time in other clinical researches; 12. Allergic constitution.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| symptom of angina pectoris; | — |
Secondary
| Measure | Time frame |
|---|---|
| Seattle angina scale score;EQ-5D health scale;TIMI risk score;Incidence of cardiovascular and cerebrovascular events; | — |
Countries
China
Contacts
Public ContactLi Xiaoying
General Hospital of PLA
Outcome results
None listed