Effects of intensive insulin therapy on type 2 diabetes

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-17010338

Enrollment

Unknown

Registered

2017-01-05

Start date

2017-01-06

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetes

Interventions

A:Lispro+Metformin

B:Insulin Aspart+Metformin

C:Insulin Aspart

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) patients with diabetes with aged 18 to 80 years; 2) HbA1c values >9.0% at diagnosis.

Exclusion criteria

Exclusion criteria: 1. serum creatinine levels =1.5 mg/dL (males), =1.4 mg/dL (females) or abnormal creatinine clearance; 2. known hypersensitivity to metformin; 3. acute or chronic metabolic acidosis, including diabetic ketoacidosis, with or without coma.

Design outcomes

Primary

Measure	Time frame
blood glucose;	—

Secondary

Measure	Time frame
HBA1c;Glycated albumin;insulin;C-reactive protein;glucagon;blood routine examination;routine urine test;liver function;	—

Countries

China

Contacts

Public ContactJianhua Ma

Nanjing First Hospital, Nanjing Medical University

majianhua@china.com+86 025-86621776

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 25, 2026