Effects of dexmedetomidine and propofol on stress response in abdominal surgery in intensive care unit

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-17010328

Enrollment

Unknown

Registered

2017-01-04

Start date

2017-01-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

abdominal surgery

Interventions

propofol groups:propofol

dexmedetomidine groups:dexmedetomidine

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 80 patients aged 18 to 80 years, undergo mechanical ventilation after abdominal surgery from November 2016 to April 2017

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating women; 2. Ejection fraction of less than 30%; 3. Bradycardia or Atrioventricular block II-III; 4. Acute coronary syndrome; 5. Renal Failure; 6. Liver function C-class; 7. Long-term use of glucocorticoid in patients; 8. History of COPD.

Design outcomes

Primary

Measure	Time frame
APACHE?;Blood gas analysis;CRP;Cortisol;ACTH;CD3;IgG, IgM;blood sugar;White blood cell count levels;Mechanical ventilation time;ICU in - hospital mortality;hospital mortality;	—

Countries

China

Contacts

Public ContactZhao Mingyan

The First Affiliated Hospital of Harbin Medical University

mingyan1970@126.com+86 13796118989

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026