The influence of saxagliptin as add-on therapy to premixed insulin on the glucolipid metabolism in elderly, insulin-requiring patients with type 2 diabetes mellitus.

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-17010318

Enrollment

Unknown

Registered

2017-01-04

Start date

2017-01-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 2 diabetes

Interventions

observation group:saxagliptin plus to insulin

control group:insulin

Eligibility

Sex/Gender

All

Age

65 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Age greater than or equal to 65 years; 2. Always have lifestyle intervention and has been the use of premixed insulin 30 r more than 12 weeks, but a poor blood sugar control; 3. HbA1c:between 6.5% and 10.0%; 4. Good compliance.

Exclusion criteria

Exclusion criteria: T1DM; Pregnancy or lactation plan the next six months pregnant women;anemia; Patients with cardiocerebrovascular events; Patients with ketosis;cancer; Stress/infection;Patients with anorexia nervosa and gastrointestinal short circuit operation; Severe heart liver kidney and gastrointestinal disorders; Research before the administration of drugs affect carbohydrate steady-state.

Design outcomes

Primary

Measure	Time frame
pancreatic function;lipids;body fat percentage;	—

Secondary

Measure	Time frame
inflammatory marks;body weight;	—

Countries

China

Contacts

Public ContactXu Yan

Peking University Shougang Hospital

xuyan9250@163.com+86 18811089567

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026