Helicobacter pylori infection
Conditions
Interventions
A:SOMAC
B:Pantoloc
C:Takepron
D:Nexium
E:Pariet
F:SOMAC+probiotic
G:none
Sponsors
Department of Gastroenterology, Sir Run Run Shaw Hospital, School of Medicine,Z hejiang University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) male or female, aged 18-70 years; 2) has undergone gastroscopy within 1 month prior to enrollment and had a complete gastroscopy and gastric mucosal biopsy data; 3) experimental group: the biopsy result showed Hp (+) and met the diagnostic criteria of chronic gastritis; Control group: both the biopsy result and 13C- urea breath test result showed Hp (-) and met the diagnostic criteria of chronic gastritis.
Exclusion criteria
Exclusion criteria: 1) patients with previous Hp eradication treatment failure; 2) patients with confirmed or suspected upper gastrointestinal malignant tumor with gastroscopy and tissue biopsy or those who can not be ruled out ; patients with peptic ulcer or other upper gastrointestinal lesions; 3) patients who have taken antacids, prokinetic drugs or gastric mucosal protective agents within two weeks prior to enrollment; 4) use of antibiotics or probiotics within one month prior to enrollment; 5) past history of gastric surgery or intestinal disease; 6) decompensated cardiac, liver, renal or pulmonary illness; 7) patients with thyroid disease or diabetes mellitus; 8) pregnant and lactating women; 9) patients who can not be scheduled follow-up or those who can not cooperate with the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| total effective rate;Hp eradication rate;cost-effect ratio; | — |
Countries
China
Contacts
Public ContactLong Yanqin
Department of Gastroenterology, Sir Run Run Shaw Hospital, School of Medicine,Z hejiang University
Outcome results
None listed