oral lichen planus
Conditions
Interventions
Experimental group:Total Glucosides of Paeony Capsules combined with prednisone for the treatment of oral lichen planus
controlled group :treat oral lichen planus with prednisone alone
Sponsors
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Older than 18 years old; 2. Patients who were diagnosed as Oral Lichen Planus by history,clinical manifestations and pathological examination ; Visual Analogue Scale(VAS) score=1; 3. Patients who are willing to participate in the test and follow-up on time; 4. Written informed consent was obtained from each patient prior to study enrollment.
Exclusion criteria
Exclusion criteria: 1. Patients who are allergic to related drugs; 2. Any other oral mucosa disease; Patients with Oral Lichen Planus that have no symptom ,cancerous lesion; 3. Patients with severe systemic diseases, tumors; 4. Participated in other clinical subjects for nearly three months; 5. Lesion that maybe induced by some medicines or Silver amalgam; 6. Pregnant women or prepare for pregnancy; 7. Patients who don't follow the doctor's advice or can't follow-up on time; 8. Patients with chronic systemic diseases,who take some medicines regularly, such as antibiotics, hormone, nonsteroidal anti-inflammatory drugs, immunosuppressants, immune enhancer,cytotoxic drugs and anticoagulant drugs; 9. Alcoholist, smokers or drug abuser; 10. mental disorder.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| effective rate of treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| lesion area;The degree of pain(Visual Analogue Scale,VAS);The recurrence rate; | — |
Countries
China
Contacts
Public ContactGuoyao Tang
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed