Immune Thrombocytopenia
Conditions
Interventions
Treatment Group:Chinese herbal granule pieces of SQSB decoction
Control Group:Placebo of simulated herbal granule pieces
Sponsors
Shanghai Municiple Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Meeting the diagnostic criteria of Immune Thrombocytopenia(ITP), and TCM pattern is Deficiency of both Qi and Yin based on syndrome differentiation; (2) Aged 18 to 65 years; (3) Platelet count detected twice in succession to be below normal(100×10^9/L), and =30×10^9/L; (4) untreated with corticosteroid or unresponded to 4-week standard dose of corticosteroid treatment; (5) Maintenance dose of corticosteroid <15mg / day (converting according to the equivalent dose of prednisone); (6) Willing to sign on the informed consent.
Exclusion criteria
Exclusion criteria: (1) Secondary thrombocytopenic purpura; (2) Meeting western diagnostic criteria, but the TCM syndrome is not Deficiency of both Qi and Yin pattern; (3) Allergic constitution or allergic to multiple drugs; (4) Pregnant or lactating women; (5) Severe mental disease; (6) Have or suspected to have a history of abuse of alcohol or drug ; (7) Abnormal liver or kidney function (serum level of alanine aminotransferase > 2 times upper normal limit, creatinine > 125umol/L); (8) Active bleeding (daily blood loss = 50ml)within latest one week; (9) Taking other Chinese medicine within latest four weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Platelet count;TCM symptom score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life assessment; | — |
Countries
China
Contacts
Public ContactQi Hu
Shanghai Municiple Hospital of Traditional Chinese Medicine
Outcome results
None listed