Comparison between different contrast media on Contrast-Induced Acute Kidney Injury in AMI patients undergoing primary percutaneous coronary intervention

Comparison of iodixanol and iohexol on Contrast-Induced Acute Kidney Injury in AMI patients undergoing primary percutaneous coronary intervention

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-16010141

Enrollment

Unknown

Registered

2016-12-12

Start date

2015-07-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Contrast-Induced Acute Kidney Injury

Interventions

iodixanol:iodixanol will be administered during PCI

iohexol:iohexol will be administered during PCI

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Men or women aged >18 years; 2. Patients with Acute Myocardial Infarction presenting within 12 hours after the onset of symptoms (18 hours in case of cardiogenic shock,or within 24 hours after thrombolysis), who are scheduled to undergo primary PCI; 3. Patients who have signed and dated the written informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients in pregnancy or lactation; 2. Long-term dialysis or severe renal dysfunction(CKD4-5); 3. Intra-arterial or intravenous administration of iodinated contrast medium from 7 days before to 72 hours after the administration of study drug; 4. Intake of any nephrotoxic medications 24 hours before or after the administration of study drug.

Design outcomes

Primary

Measure	Time frame
Incidence of CI-AKI;	—

Secondary

Measure	Time frame
MACE;proportion of patients with severe acute renal failure and dialysis;	—

Countries

China

Contacts

Public ContactXiang Dingcheng

Department of Cardiology, General Hospital of Guang Zhou Military Command

dcxiang@foxmail.com+86 13609008024

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026