vitiligo
Conditions
Interventions
Minocycline Group:oral Minocycline
Glucocorticoid Group:oral Minocycline
Simvastatin Group:oral Simvastatin
Placebo Group:oral Placebo
Sponsors
Shanghai Dermatology Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 70 years old; 2. identify vitiligo; 3. Above, a history of more than 1 year, in the course of the disease at least taken: (1) local external use potent corticosteroids; (2) system application of glucocorticoid hormone; (3) PUVA; (4) narrow wave ultraviolet ray; (5) 308 excimer laser; (6) melanin cell transplantation, two or more treatments; 4. Not used any treatment could impact the present study before recruitment; 5. no serious liver and kidney and blood system diseases; 6. the patients agree to and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients in progressive stage: severe heart renal insufficiency, diabetes, high blood pressure, tuberculosis, and hepatitis b and other infectious diseases; 2. Patients with plateau: have scar constitution; 3. With severe mental illness, do not have independent ability; 4. the test drug allergy or intolerance; 5. Pregnancy or breast-feeding women, or ready to pregnant women; 6. In recent 3 months, participated in other clinical trials; 7. Any medical history, according to the researchers may interfere with the test results or increase the risk of the subjects; 8. compliance is bad, not strictly carry out the plan.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| size of lesion; | — |
Countries
China
Contacts
Public ContactYeqiang Liu
Shanghai Dermatology Hospital
Outcome results
None listed