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The effect on dose-response of adding dexmedetomidine to intrathecal bupivacaine in spinal anesthesia for ceasarean delivery

The effect on dose-response of adding dexmedetomidine to intrathecal bupivacaine in spinal anesthesia for ceasarean delivery: A prospective, double blinded, randomised study.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-16009699
Enrollment
Unknown
Registered
2016-11-01
Start date
2016-11-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean Section

Interventions

Dex Group: 5 mcg dexmedetomidine+ bupivacaine

Sponsors

Jiaxing Maternity and Child Care Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists physical class I or II, scheduled for elective ceasarean delivery, were enrolled in this study.

Exclusion criteria

Exclusion criteria: Patients with obesity (body mass index (BMI) > 35 kg/m2), gestational age < 37 weeks, active labor, early labor, ruptured membranes, history of previous cesarean deliveries, diabetes or gestational diabetes, hypertension or pre-eclampsia, intrauterine growth restriction, placenta previa, significant coexisting maternal disease, any contraindication to spinal or epidural anesthesia such as local infection or bleeding disorders.

Design outcomes

Primary

MeasureTime frame
Effective dose of bupivacaine;ineffective dose of bupivacaine;

Secondary

MeasureTime frame
the duration of spinal analgesia;the onset time of sensory block;the duration of sensory block;the onset time of motor block;the duration of motor block;The requirement of rescued analgesic postoperative 24 h;grade the level of satisfaction;

Countries

China

Contacts

Public ContactFei Xiao

Jiaxing Maternity and Child Care Hospital

13706597501@163.com+86 13706597501

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 6, 2026