lung injury induced by CPB
Conditions
Interventions
XBJ group:Xuebijing injection
Sponsors
Department of Anesthesiology, the Second Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
All
Age
25 Years to 65 Years
Inclusion criteria
Inclusion criteria: 50 patients with CPB, ASA II-III, heart function II-III, aged 25 to 65 years old.
Exclusion criteria
Exclusion criteria: Severe lung disease or lung dysfunction, patients with immune dysfunction,toxemia, pleural effusion, lung infection, hypoproteinemia, patients with hepatic, renal or coagulation disorder, COPD and asthma were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PaO2/FiO2 at 24 h post-operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of ventilation in ICU;Time of stay in ICU;Length in hospital;IL-1 in BALF;IL-8 in BALF;IL-10 in BALF;CRP in BALF;neutrophil elastase;neutrophil counts in BALF;IL-10 in serum;IL-1 in serum;IL-8 in serum;CRP in serum; | — |
Countries
China
Contacts
Public ContactGao Wei
Department of Anesthesiology, the Second Affiliated Hospital of Harbin Medical University
Outcome results
None listed