Minimal Hepatic Encephalopathy
Conditions
Sponsors
Shuguang Hospital affiliated to Shanghai university of traditional Chinese medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) The person who has hepatitis B, hepatitis C, alcohol, or autoimmune liver cirrhosis; 2) The person who doesn't have abnormal signs of clinical mental and nervous system disease; 3) The diagnosis of liver cirrhosis reference 2014 white paper on "China liver disease diagnosis and treatment management norms" (excerpts).
Exclusion criteria
Exclusion criteria: (1) The person who has hepatic encephalopathy in the last 6 months or now; (2) The person who takes lactulose, probiotics, or nmda ornithine for nearly three months, who uses antibiotics or sedatives nearly 1 week; (3) The person who has alcoholic liver cirrhosis and alcohol abuse nearly three months; (4) The person who has color blindness, cataracts, diabetes, or hypertension retinopathy, near vision disorder; (6) The person who has a history of mental illness, mental disease or nerve disease; (7) The person who has other metabolic disease, such as ketoacidosis, hypoglycemia, hyponatremia and renal encephalopathy, alcoholic encephalopathy, Pulmonary encephalopathy, wernicke encephalopathy; (8) acute poisoning, etc; (9) The person who has other systems such as heart, lung, and kidney of serious illness; (10) The person who doesn't cooperate with diagnosis and treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number connection test;Digit symbol test;Metabonomics;genomics; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood ammonia; | — |
Countries
China
Contacts
Public ContactMingyu Sun
Shuguang Hospital, Shanghai University of TCM
Outcome results
None listed