Gynecology cancer-related anemia
Conditions
Interventions
Experimental group 1 (low level of erythropoietin):Subcutaneous injection of recombinant human erythropoietin+Intravenous iron therapy
Experimental group 2 (low level of erythropoietin):Subcutaneous injection of recombinant human erythropoietin+Oral iron therapy
Experimental group 3(erythropoietin is normal):Intravenous iron therapy
Experimental group 4(erythropoietin is normal):Oral iron therapy
Control group 1:Intravenous iron therapy
Control group 2:Oral iron therapy
Sponsors
The First Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged elder than 18 years, ECOG score 0, 1, or 2; 2. Hb<100 g/L; MCV<80fl; MCHC<32%; SI<8.95umol/L; sFer<800ug/L; ATST<50%; 3. It is not used within 10 days of iron treatment before, treatment without prior history of blood transfusion within 30 days, without erythropoietin treatment history, no history of corticosteroid therapy.
Exclusion criteria
Exclusion criteria: 1. Anemia caused by other reasons (such as gastrointestinal bleeding or blood shortage of raw materials such as metabolic disorders) or with blood diseases; 2. Suspicion or diagnosis of bone metastases in patients with brain metastases to check the liver and kidney function of heart function were normal without hypertension coronary heart disease, etc.; 3. Expected survival time> 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood routine; | — |
Secondary
| Measure | Time frame |
|---|---|
| sEPO;serum iron;serum ferritin;serum transferrin;serum transferrin saturation;serum folic acid;vit B12; | — |
Contacts
Public ContactShen Huimin
The First Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed