recurrent spontaneous abortion with thrombophilla
Conditions
Interventions
LMWH plus LDA Group:LMWH plus LDA
LDA Group:LDA
LMWH group:Low molecular weight heparin
Sponsors
Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine
Eligibility
Sex/Gender
Female
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: Woman who had their Second miscarriage before 12(th) week of gestation.The patient who is diagnosed as thrombophilia with recurrent pregnancy loss. Signed consent form.
Exclusion criteria
Exclusion criteria: 1. having experiencedsevere allergies, trauma history and/or operation history within 3 months; 2. with a history of mental illness and/or family history of mental illness; 3. limb disabled; 4. taking medicine within one month; 5. suffering major events or having mood swings; 6. with a history of recurrent pregnancy loss; 7. having internal and surgical disease(after having variety of physical examination such as electrocardiogram/hepatic and renal function/blood routine and urine rotine); 8.chromosome aberrations in anyone of the couple. 9.having contraindications to asprin and low molecular weight heparin.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fetus chromosome;antithrombin, AT;protein C;protein S;D-Dimer;Factor V Leiden Mutation;MTHFR C677T Mutation;PAI-1 4G/5G Mutation;Factor XIII V34L Mutation;Anti-cardiolipin antibodies;Anti-ß2 Glycoprotein I Antibodies; | — |
Countries
China
Contacts
Public ContactBao Shihua
Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine
Outcome results
None listed