Diminished ovarian function
Conditions
Interventions
The experimental group:Heyan Kuntai capsule+conventional therapy
The control group:Placebo+conventional therapy
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
Female
Age
25 Years to 42 Years
Inclusion criteria
Inclusion criteria: 1. Aged 25-42 years old; 2. 0.5 ng/ml < anti-mullerian hormone (AMH)<1.1 ng/ml; 3. 10 mIU/ml= follicle stimulating hormone (FSH)<30 mIU/ml; 4. Voluntary partcipants, and agreed to sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients diagnosed with premature ovarian failure (bFSH=40 mIU/ ml); 2. endometriosis, adenomyosis, endometrial lesions (submucosal fibroids, endometrial polyps, etc.), uterine muscle tumors> 4 cm; 3. for patients with fertility requirements: genetic factors, tubal factors, congenital birth defects or abnormal development, or male's factors caused infertility; 4. patients underwent hysterectomy; 5. allergic; 6. serious primary cardiovascular, liver, kidney, hematopoietic system, and mental diseases; 7. patients who are participating in other clinical trials, or participated in other clinical trials within the past month; 8. suspected or indeed alcohol, drug abuse history; or patients who have other complicated diseases or conditions, such as frequent changes in the working and living environment to cause low compliance; 9. patients taking cold medicine during the treatment; 10. the investigators identified patients unsuitable for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Antral follicle count (AFC);Anti-mullerian hormone (AMH); | — |
Secondary
| Measure | Time frame |
|---|---|
| Follicle stimulating hormone (FSH);Luteinizing hormone (LH);Estradiol (E2);Pregnancy rate; | — |
Countries
China
Contacts
Public ContactYu Qi
Peking Union Medical College Hospital
Outcome results
None listed