Granisetron given intravenously could decrease the incidence of spinal-induced hypotension during elective ceasarean section

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-16009107

Enrollment

Unknown

Registered

2016-08-28

Start date

2016-09-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spinal-anesthesia induced hypotension

Interventions

Granisetron Group:Granisetron Given intravenously

control group:saline given intravenously

Eligibility

Sex/Gender

Female

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. aged from 18 to 35 years old; 2. gestation between 37 to 42 weeks; 3. American Society of Anesthesiologists(ASA) physical status I or II in preoperative patient assessment; 4. prenatal examinationhepatic and renal function were normalwithout a history of heart and long disease; 5. the fetus is normal; 6. single gestation.

Exclusion criteria

Exclusion criteria: 1. hypertension (SBP>140mmHg or DBP>90mmHg); 2. BMI>25kg/m2; 3. placenta previa; 4. fetus grow abnormal; 5. intraspinal anesthesia contraindication; 6. patients who had taken 5-HT receptor antagonist recently; 7. 5-HT receptor antagonist contraindication.

Design outcomes

Primary

Measure	Time frame
incidence of spinal-induced hypotension;incidence of spinal-induced bradycardia;	—

Countries

China

Contacts

Public ContactZhou Wenqin

West China Second Hospital, Sichuan University

zhoutry@qq.com+86 18228069886

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026