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Clinical study on the effect of Xiaojin pills combined with levothyroxine in the treatment of breast cancer patients with thyroid nodule.

Clinical study on the effect of Xiaojin pills combined with levothyroxine in the treatment of breast cancer patients with thyroid nodule.

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-16009046
Enrollment
Unknown
Registered
2016-08-19
Start date
2016-08-25
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer

Interventions

Group 1:Xiaojin pills monotherapy
Group 2:levothyroxine monotherapy
Group 3::Xiaojin pills and levothyroxine combination therapy

Sponsors

Department of Endocrine and Breast Surgery of the First Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosis as breast cancer according to clinical practice guideline; 2. Performed the operation and all cycles of chemotherapy; 3. Volunteered for this study and informed consent was abtained from the participants; 4. Aged between 18 and 75 years old; 5. Detected thyroid nodule by color Doppler ultrasonography, whether single nodule or multiple nodules, and the nodules <2cm with clear margin and without malignant signs; 6. Normal thyroid function; 7. Informed consent was abtained from the participants.

Exclusion criteria

Exclusion criteria: 1. Those who havent finished systemic treatment of breast cancer; 2. Thyroid dysfunction; 3. Those whos thyroid malignant cant be ruled out by color Doppler ultrasonography; 4. Coexistence of other serious medical conditions, such as serious infections, organs failure, serious injury, etc.; 5. Pregnant women; 6. Allergic to Xiaojin pills; 7. Liver function and renal function dysfunction(the values higher than one time of normal).

Design outcomes

Primary

MeasureTime frame
Cure rate;Excellent rate;Effective rate;Ineffectiveness rate;Total effective rate;

Secondary

MeasureTime frame
Side effects;

Countries

China

Contacts

Public ContactRen Guosheng; Kong Lingquan

Department of Endocrine and Breast Surgery of the First Affiliated Hospital of Chongqing Medical University

huihuikp@163.com+86 13101380893

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026