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Randomized clinical trial of the effect of preoperative oral carbohydrate on postoperative intestinal barrier function after colorectal surgery

Randomized clinical trial of the effect of preoperative oral carbohydrate on postoperative intestinal barrier function after colorectal surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-16008918
Enrollment
Unknown
Registered
2016-07-26
Start date
2016-08-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal carcinoma

Interventions

Experimental group:Preoperative night and preoperative 2 h drink multidimensional carbohydrate supplementation 700 ml, 350 ml, respectively
Control group:Preoperative fasting 12h, 4h drink ban
pure water group:Preoperative night and preoperative 2 h drink pure water 700 ml, 350 ml, respectively

Sponsors

Affiliated Hospital of North Sichuan Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 79 Years

Inclusion criteria

Inclusion criteria: patients scheduled for laparoscopic colorectal surgery; aged 45~79 years; BMI 20~30.

Exclusion criteria

Exclusion criteria: Exclusion criteria were diabetes mellitus or impaired glucose tolerance, medication affecting insulin sensitivity; weight loss greater than 10 percent during the previous 6 months; signs of distant metastasis; conditions (including pharmacological treatment) known to affect gastric emptying rate; accompanied by severe brain, heart, pulmonary, liver and kidney disease; with severe anemia and hypoalbuminemia.

Design outcomes

Primary

MeasureTime frame
Diamine oxidase, D - lactic acid;FBG;GLP-1, GIP;TNF-a, IL-6;

Secondary

MeasureTime frame
The time of first passage of flatus;The time of first bowel movement;

Countries

China

Contacts

Public ContactYoubo Zuo

Affiliated Hospital of North Sichuan Medical College

13808271734@163.com+86 13808271734

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026