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Prevention and treatment of estrogen therapy on the perimenopausal diseases of multi-center study in China

Prevention and treatment of estrogen therapy on the perimenopausal diseases of multi-center study in China

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-16008754
Enrollment
Unknown
Registered
2016-07-01
Start date
2016-07-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

menopaual syndrome

Interventions

control group:placebo

Sponsors

The Sixth People' Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
40 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged 40 ~ 60 years; 2. taking no estrogen therapy in the past three months; 3. FSH > 40 IU/L; 4. without pregnancy; 5. comply with the plan and follow-up on time; 6. understanding test content, signed informed consent; 7. normal or mild menopausal syndrome, mood disorders KMI scale, depression scale, PSQI scale score; 8. normal or mildly bone loss by bone mineral density; 9. normal blood fat; 10. without serious heart and kidney disease; 11. without contraindications to estrogen therapy, such as breast cancer.

Exclusion criteria

Exclusion criteria: 1. taking estrogen or other steroid hormone drugs the recent three months; 2. with malignant tumor; 3. serious mental disorders; 4. difficult understanding the experiment content and sign the informed consent; 5. pregnancy; 6. serious nerve dysfunction; 7. the expectant survival < 2 years; 8. joining other studies at the experimental period; 9. hypertension, hyperglycemia, hyperlipidemia, cardiovascular disease, ovarian disease.

Design outcomes

Primary

MeasureTime frame
Menopause scale;BMD;Stroke rate;

Countries

China

Contacts

Public ContactTao Minfang

The Sixth People' Hospital

taomf@sjtu.edu.cn+86 18930177770

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026