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A single-center, prospective, randomized controlled trial of thalidomide plus CHOP-like regimen on newly diagnosed aggressive T-cell lymphoma

A single-center, prospective, randomized controlled trial of thalidomide plus CHOP-like regimen on newly diagnosed aggressive T-cell lymphoma

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-16008640
Enrollment
Unknown
Registered
2016-06-13
Start date
2016-07-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aggressive T-cell lymphoma

Interventions

one:thalidomide plus CHOP-like regimen
two:CHOP-like chemotherapy

Sponsors

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients must meet the following criteria for study entry: 1. Any Sex; Unpregnancy; 2. Aged 18 to 75 years old; 3. All patents are diagnosed by pathology; 4. ECOG performance status of 0-1; 5. No abnormality of liver and kidney function; 6. No serious complications of severe systemic infection, severe anemia and cachexia; 7. On their own or someone else to fill in the complete scale; 8. Agreed to participate in this study.

Exclusion criteria

Exclusion criteria: Patients who meet any of the following criteria will be excluded from study entry: 1. Childbearing age and recent family planning women; 2. involved other cancer therapy clinical trials; 3. Thalidomide or within any chemotherapy drug allergy; 4. Patients with mechanical gastrointestinal obstruction; 5. With other serious systemic diseases; 6. There is a history of thromboembolism, except caused by PICC.

Design outcomes

Primary

MeasureTime frame
Progression-Free Survival;Total efficiency;Overall survival;

Secondary

MeasureTime frame
complete response;partial response;

Countries

China

Contacts

Public ContactGang Wu

Union Hospital,Tongji Medical College,Huazhong University of Science and Technology

xhzlwg@163.com+86 13871240042

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026