pain
Conditions
Interventions
D group:dexmedetomidine and remifentanil
Sponsors
Liaocheng People’s Hospital, Liaocheng,Shandong province
Eligibility
Sex/Gender
All
Age
45 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 45 to 65 years; 2. American Society of Anesthesiologists physical status II-III; 3. Glasgow Coma Scale score>=13.
Exclusion criteria
Exclusion criteria: 1. A history of craniotomy; 2. Heart disease (heart rate<=50 bpm); 3. Severe hypertension (systolic blood pressure=180 mmHg or diastolic blood pressure=110 mmHg); 4. A history of lung disease (peripheral capillary oxygen saturation [SpO2] < 93% when breathing air in the awake state); 5. A history of liver or kidney dysfunction; 6. Hypersensitivity (allergic) or intolerance to dexmedetomidine or remifentanil; 7. Body weight beyond ± 15% of the standard body weight; 8. Suspected postoperative intracranial hemorrhage; 9. Study termination by the researchers from a medical perspective or the patients refusal to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vital signs;Vasoactive drugs; | — |
Secondary
| Measure | Time frame |
|---|---|
| the scores of pain;Ramsay score;ICU residence time;Adverse reactions; | — |
Countries
China
Contacts
Public ContactChunguang Ren
Liaocheng People's Hospital, Liaocheng, Shandong
Outcome results
None listed