central serous chorioretinopathy
Conditions
Interventions
I(acute CSC):observation
II(acute CSC):oral spironolactone
III(chronic CSC):oral spironolactone
Sponsors
The First Affiliated Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.FFA showing a focal leak at the level of the RPE,a subretinal detachment of the retinal photoreceptors from the RPE layer was demonstrated by spectral-domain OCT; 2.patients aged >=18 years; 3.existence of subretinal fluid (SRF) with subjective symptoms such as decreased vision or metamorphopsia.
Exclusion criteria
Exclusion criteria: 1. current pregnancy; 2. history of taking corticosteroids or related drugs; 3. systemic diseases such as endogenous hypercortisolism, and diabetic; 4. Macular disorders such as idiopathic choroidal neovascularization, polypoidal choroidal vasculopathy, and age-related macular degeneration were excluded from the study; 5. eyes with a history of previous treatment, including macular photocoagulation, photodynamic therapy, or intravitrealantivascular endothelial growth factor injection, also were excluded; 6. High blood pressure, diabetes, hyperlipidemia and other systemic diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BCVA;OCT;aldosterone level; | — |
Countries
China
Contacts
Public ContactQinghuai Liu
The First Affiliated Hospital of Nanjing Medical University
Outcome results
None listed