diabetes
Conditions
Interventions
vitamin D intervention group:Vitamin D3
control group:No intervention
Sponsors
Gansu Provincial Hospital
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Type 2 diabetes based on WHO (1999) criteria for diabetes (FBG>=7.0mmol/L,2hPBG>=11.1mmol/L); 2. 25(OH)D3 insufficiency (serum level of 25(OH)D3< 30ng/ml; 3. Albuminuria ( the 24h urine albumin excretion rate 20 200ug/ min).
Exclusion criteria
Exclusion criteria: 1. Type 1 diabetes, gestational diabetes, other specific type of diabetes or secondary diabetes; diabetes associated with stressful condition such as infection, diarrhea, stroke and heart failure; diabetes associated with diabetic ketoacidosis or hyperglycemic hyperosmolar syndrome; 2. Patient who has the history of taking vitamin D, statins, angiotensin-converting enzyme inhibitors, rosiglitazone, angiotensin receptor blockers, or glucocorticoids in three months; 3. Hypercalcemia, kidney stone or urine tract stonesarcoidosis, osteomalacia, primary hyperparathyroidism, liver and renal dysfunction; malignant tumor or connective tissue diseases; 4. Patient who is attending or will attend another clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemoglobin A1c;UAER;25(OH)D3;Toll like receptor 4;Carotid artery elasticity index;inflammatory cytokines;fasting glucose;triglyceride;HDL;LDL;serum calcium;serum phosphate; | — |
Countries
China
Contacts
Public ContactJinxing Quan
Gansu Provincial Hospital
Outcome results
None listed