Sedation after cardiac surgery
Conditions
Interventions
Control group:Propofol
Sponsors
The First Affiliated Hospital, School of Medicine Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to 150 Years
Inclusion criteria
Inclusion criteria: 1. aged 18 years or older; 2. selective cardiac surgery; 3. Admitted to intensive care unit and received invasive mechanical ventilation; 4. lack of prior AF or flutter before receiving sedation in the ICU; 5. Informed consent was obtained.
Exclusion criteria
Exclusion criteria: 1. acute severe neurological disorder; 2. mean arterial pressure less than 55mmHg despite appropr-iate intravenous volume replacement and vasopressors; 3. heart rate less than 50/min; 4. atrioventricular-conduction grade II or III (unless pacemaker installed); 5. of dexmedetomidine or propofol allergy or other contradications.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Delirium;Infection;Length of hospital stay;Mechanical ventilation time;One year mortality; | — |
Primary
| Measure | Time frame |
|---|---|
| Onset and time of postoperative atrial fibrillation;Acute kidney injury;Postoperative length of hospital stay;Length of ICU stay;Hospital fees;Patients' mortality;APCHEII score;SOFA score; | — |
Countries
China
Contacts
Public ContactXiangming Fang
The First Affiliated Hospital School of Medicine Zhejiang University
Outcome results
None listed