The blood loss and pain after total knee arthroplasty
Conditions
Interventions
Cocktail Group:Intravenous plus topical infusion hemostatic drugs and topical infusion pain relievers
Control group :Topical infusion hemostatic drugs and topical Infiltration pain relievers
Sponsors
China-Japan Friendship Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18-70 years old, sex is not limited; 2. The patients with severe osteoarthritis performed by primary unilateral cemented TKA. 3. All patients were required to sign an informed consent prior to participation in the study.
Exclusion criteria
Exclusion criteria: If they were more than 70 years old or made habitual use of opioids, had inflammatory joint disease, or had previous fracture of the affected knee, or alternatively, Hemostatic drugs and pain relievers was contraindicated or not technically possible. Revision surgery, bilateral joint arthroplasty, known hypersensitivity to TXA or its ingredients, active intravascular clotting disorders, and acute subarachnoid hemorrhage.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood loss (including hidden blood loss);pain score (VAS); | — |
Secondary
| Measure | Time frame |
|---|---|
| HSS(the hospital for special surgery) Score;Hemoglobin Change; | — |
Countries
China
Contacts
Public ContactFuqiang Gao
China-Japan Friendship Hospital
Outcome results
None listed