The effect of thoracic paravertebral block on chronic pain in the breast cancer patients: a randomized controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-16008127

Enrollment

Unknown

Registered

2016-03-22

Start date

2016-04-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative chronic pain

Interventions

Intervention Group:paravertebral thoacic block combined general anesthesia

Control Group:general anesthesia only

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1) Aged 18 years and above, ASA I-III stage; 2) Primary breast cancer, planned surgery, including modified radical mastectomy, breast conserving surgery, sentinel lymph node biopsy.

Exclusion criteria

Exclusion criteria: 1) Previous thoracic surgery,incision greater than 2cm; 2) Emergency surgery or palliative surgery; 3) Previous use of ropivacaine in patients allergic or manual contraindication; 4) Paravertebral thoacic block anesthesia contraindications, including infection of puncture or intrathoacic, tumor invasion of puncure,history of severe spinal deformity or spinal surgery,Abnormal coagulation function (PT or APTT>=1.5 ULN), PLT<100*10^9/L, Severe respiratory disease, Diaphragmatic paralysis.

Design outcomes

Primary

Measure	Time frame
incidence of postoperative chronic pain;	—

Secondary

Measure	Time frame
requirement of anesthetic;anesthesia related complication;the quality of life and depression/anxiety state after 6 months;	—

Countries

China

Contacts

Public ContactWang Dong-xin

Peking University First Hospital

wangdongxin@hotmail.com+86 13910731903

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026