Effect of Intraoperative Dexmedetomidine Infusion Combined with Sevoflurane during BIS-guided Fast Track Anesthesia for Intracranial Aneurysms Interventional Surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-IPR-16008113

Enrollment

Unknown

Registered

2016-03-17

Start date

2016-04-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intracranial aneurysm

Interventions

Group D:receive DEX (40µg/ml) 0.6µg/kg for 10 min, then change into 0.4µg/kg/h

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-60 years; 2. ASA I-II.

Exclusion criteria

Exclusion criteria: 1. Coagulation disorders; 2. Always has a history of drug allergy; 3. Patients with severe high blood pressure and cardiovascular disease; 4. Patients with liver and kidney function is not complete; 5. Preoperative 2 d taking sedatives; 6. Patients with sinus bradycardia.

Design outcomes

Primary

Measure	Time frame
IL-6;IL-8;IL-10;TNF-a;SOD;MDA;IL-1ß;blood glucose;NSE;S100ß;	—

Countries

China

Contacts

Public ContactTANG CHAOLIANG

Southern District of Anhui Provincial Hospital

tangruoxiao2012@hotmail.com+86 13866777142

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 2, 2026