Aged Functional Dyspepsia.
Conditions
Interventions
Control group:With domperidone 2 weeks, 10mg/per, tid, and 4weeks followed up.
The treatment group A:With Combizym 2 weeks, two pills each time, tid, and 4weeks followed up.
The treatment group B:The treatment group B were based on the same treatment of control group plus Combizym. During or after a meal to swallow, and 4weeks followed up.
Sponsors
CHINESE PLA GENERAL HOSPITAL
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. All genders aged >=65; 2. Include three or more indigestion symptoms ,such as epigastric painabdominal discomfort epigastrium burn feelheartburnabdominal spastic pain chest paincan't eat regularlyreflux postprandial fullness slow digestionabdominal oppressing sensationabdominal flatulenceearly satiety nausea belchingvomiting and bad breath. And there are no organic disease to explain; 3. Symptoms above >=6m before diagnose, and meets these criteria >=3m.
Exclusion criteria
Exclusion criteria: 1. Patients with severe liver, gallbladder, pancreas disease; 2. patients with chronic constipation; 3. The stomach contains organic disease, such as ulcer, tumor(within 6M); 4. Complicated with pregnancy lactationdiabetes malignant tumor, and serious heart, lung, and nephropathy. 5. Patients with history of abdominal operation, or neuropsychic diseases, the crowd with limited activity, and so on; 6. Clinical Research Physicians consider patients with unstable condition,and will affect the study effect evaluation; 7. Patients participated in other clinical studies within 4 weeks; 8. Patients was areadly addictive with or need to take other drugs in treating dynamic disturbancedyspepsi. That would effect experiment result; 9. Patients are sensitive with study drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Epigastric pain;Epigastric discomfort;Burning in epigastrium;Heartburn;Abdominal spastic pain;Chest pain;Can't eat regularly;Reflux;Postprandial fullness or slow digestion;Epigastrium oppressing sensation;Epigastrium flatulence;Early satiety;Nausea;Belching;Vomiting;Bad breath; | — |
Countries
China
Contacts
Public ContactWu Benyan
Outcome results
None listed