Dry eye after LASIK
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Between the ages of 20-30; 2. Refractive diopter between -3.0D and -6.0D before the surgery; 3. Without active eye inflammation before the surgery; 4. No symptoms before the surgery; 5. Do not use any local eye drops 2 weeks before the surgery; 6. Do not wear contact lenses 1 year before the surgery; 7. fBUT>10s and Schirmer >10mm/5min and cornea hyperemia(-) before the surgery; 8. fBUT<=5s/Schirmer I<=5mm/5min and cornea hyperemia(-) and dry eye symptoms or 5s<fBUT<=10s/ 5<Schirmer I)<=10mm/5min and cornea hyperemia(+) and dry eye symptoms 1 week after FS-LASIK surgery; 9. fBUT<=5s/ Schirmer I<=5mm/5min and cornea hyperemia(+) and dry eye symptoms 1 week after FS-LASIK surgery; 10. Without other eye complications 1 week after FS-LASIK surgery.
Exclusion criteria
Exclusion criteria: 1. Somebody can feel discomfort or adverse reaction after use the test drug; 2. Somebody has accepted any other test drug 1 month before the study or screening; 3. Somebody can occur serious dangers due to drug combination that lead to the drug interaction; 4. Somebody complicated other diseases and the researcher also think it is hard to assess or complete treatment; 5. Pregnant woman and breast feeding women; 6. Somebody are rejected by researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analogue scale;Ocular sueface disease index questionnaire;OQAS;NITBUT;Tear meniscus height;fBUT;Cornea hyperemia scoring;Schirmer? test;Cornea sensation; | — |
Secondary
| Measure | Time frame |
|---|---|
| UCVA, BUCVA; | — |
Countries
China