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0.3% versus 0.1% sodium hyaluronate eyedrops on releasing dry eye symptoms and long-term efficacy after LASIK

0.3% versus 0.1% sodium hyaluronate eyedrops on releasing dry eye symptoms and long-term efficacy after LASIK

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-16007940
Enrollment
Unknown
Registered
2016-02-17
Start date
2016-02-15
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry eye after LASIK

Interventions

0.1%sodium hyaluronate eyedrops group:using 0.3%sodium hyaluronate eyedrops

Sponsors

Tianjin Medical University Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 30 Years

Inclusion criteria

Inclusion criteria: 1. Between the ages of 20-30; 2. Refractive diopter between -3.0D and -6.0D before the surgery; 3. Without active eye inflammation before the surgery; 4. No symptoms before the surgery; 5. Do not use any local eye drops 2 weeks before the surgery; 6. Do not wear contact lenses 1 year before the surgery; 7. fBUT>10s and Schirmer >10mm/5min and cornea hyperemia(-) before the surgery; 8. fBUT<=5s/Schirmer I<=5mm/5min and cornea hyperemia(-) and dry eye symptoms or 5s<fBUT<=10s/ 5<Schirmer I)<=10mm/5min and cornea hyperemia(+) and dry eye symptoms 1 week after FS-LASIK surgery; 9. fBUT<=5s/ Schirmer I<=5mm/5min and cornea hyperemia(+) and dry eye symptoms 1 week after FS-LASIK surgery; 10. Without other eye complications 1 week after FS-LASIK surgery.

Exclusion criteria

Exclusion criteria: 1. Somebody can feel discomfort or adverse reaction after use the test drug; 2. Somebody has accepted any other test drug 1 month before the study or screening; 3. Somebody can occur serious dangers due to drug combination that lead to the drug interaction; 4. Somebody complicated other diseases and the researcher also think it is hard to assess or complete treatment; 5. Pregnant woman and breast feeding women; 6. Somebody are rejected by researchers.

Design outcomes

Primary

MeasureTime frame
Visual analogue scale;Ocular sueface disease index questionnaire;OQAS;NITBUT;Tear meniscus height;fBUT;Cornea hyperemia scoring;Schirmer? test;Cornea sensation;

Secondary

MeasureTime frame
UCVA, BUCVA;

Countries

China

Contacts

Public ContactZhao Shaozhen
Zhaosz1997@sina.com+86 022 13802036813

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026