postoperative pain
Conditions
Interventions
test group:patient-controlled intravnous analgsia with dexmedetomidine
contrast group:patient-controlled intravnous analgsia without dexmedetomidine
Sponsors
Affiliated Hospital of Nantong University.
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients with full ability to communicate undergoing selective abdominal operation with general anesthesia,including operation on stomach intestines kidneys liver with endoscope or not, ASA status I-II, aged 18~65years old, no restriction on gender, operation time 1-4 hours and awake extubated.
Exclusion criteria
Exclusion criteria: 1. Allergic to dexmedetomidine or any drugs used during this study; 2. Patients on long-term therapy with narcosis analgeticsedative or non-steroid anti-inflammatory drugs; 3. patients with neuromuscular disorders; 4. patients with endocrine system disease; 5. patients with allergic disorders; 6. patients with mental illness; 7. patients with Cardiac conduction disturbances or allorhythmia HR<50bpm, SBP<100mmHg; 8. patients with blood loss more than 600ml or secondary operation; 9. patients enrolled in other clinical test within 3 months; 10. other situations unsuitable for this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| drug consumption;drug recruitment; | — |
Secondary
| Measure | Time frame |
|---|---|
| total bolus;VAS scores;OAA scores; | — |
Countries
China
Contacts
Public ContactYongtao Gao
Outcome results
None listed