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A Prospective, Randomized,Double-blinded Comparison of Local Anesthetic Agents for Vitrectomy

A Prospective, Randomized,Double-blinded Comparison of Local Anesthetic Agents for Vitrectomy

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-16007876
Enrollment
Unknown
Registered
2016-02-02
Start date
2015-12-03
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Required vitrectomy disease

Interventions

Bupivacaine Group:0.75% Bupivacaine
Combination Group:A equal volumes combination of 0.75% bupivacaine and 2% lidocaine

Sponsors

Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Patients suffer from diabetic retinopathy, retinal detachment, central or branch retinal vein occlusion,macular epiretinal membranes and macular holes, giant retinal tear high myopia and other diseases require vitrectomy at the first time. Patients can communicate smoothly with clinicians. Subjects participates voluntarily in the trial and sign an informed consent.

Exclusion criteria

Exclusion criteria: Patients will be excluded if they are unwilling to take part, if they have communication problems or there is a history of allergy to amide-type local anaethesia agents.Patients have serious systemic disease that may affect the treatment and assessment. Patients have a vitrectomy surgery history,orbital surgeries, orbital deformities, trauma, uveitis,anterior chamber inflammation,keratitis, thinning of the corneal caused by degeneration etc. Pregnanta and lactation female patients should be excluded.

Design outcomes

Primary

MeasureTime frame
Time of onset of analgesia;Time of onset of akinesia;Duration of anesthesia;

Secondary

MeasureTime frame
Pain and sports scores at 24 hours after surgery;Pain and sports scores at 48 hours after surgery;

Countries

China

Contacts

Public ContactZhaoyang Wang
zhaokekewzy@hotmail.com+86 15921108602

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 27, 2026