Comparison of ropivacaine, ropivacaine-morphine, ropivacaine-dexmedetomidine for interscalene brachial plexus block: A prospective, randomized, double-blinded, comparative study
Conditions
Interventions
ropivacaine mixed with dexmedetomidine group:ropivacaine mixed with dexmedetomidine
and ropivacaine mixed with morphine group:ropivacaine mixed with morphine
Sponsors
The Second Affiliated Hospital of Wenzhou Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 90 patients with American Society of Anesthesiologists (ASA) physical status I/II who were scheduled for upper extremity surgery under brachial plexus block was to be used were enrolled in this prospective, doubleblind, controlled trial.
Exclusion criteria
Exclusion criteria: (1) to test suspected drug allergy; (2) in patients weighing more than 100kg; (3) preoperative New York Heart Association (NYHA) class III or IV persons; (4) Consolidated heart, liver, kidney, hematopoietic system and other vital organs and systems of serious primary disease or ALT, more than 2 times of the upper limit of normal AST level, Cr exceeds the upper limit of normal level; (5) preoperative hemoglobin 160g/L, or hematocrit <30% significantly; preoperative platelet count <=100* 10^9/L persons; preoperative coagulation prompt PT or APTT greater than the upper limit of normal by 1.5 times; (6) Liquid overload, including pulmonary edema; (7) serum K+, Na+, Mg2+, Cl- abnormalities; (8) with severe systemic infection; (9) associated with neurological and psychiatric disorders while not cooperate or unwilling collaborators; (10) during pregnancy, lactation or recent fertility planner; (11) within the past three months those who participated in other clinical trials; (12) The researchers consider it appropriate to participate in the clinical trial were.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Onset time of sensory block;Duration of sensory block;Onset time of motor block;Duration of motor block; | — |
Countries
China
Contacts
Public ContactWang Xiaocou
Outcome results
None listed