Ischemic stroke
Conditions
Interventions
Group of fluoxetine used in 20mg per day: fluoxetine used in 20mg per day
Group of fluoxetine used in 10mg per day:fluoxetine used in 10mg per day
Sponsors
The Shenzhen People's hospital, Shenzhen, Guangdong, China
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Adherence to the diagnostic criteria of ischemic stroke as defined by World Health Organization (WHO); (2) first onset of stroke within 1 week; (3) 18–80 years old; (4) symptoms of defective nervous system and National Institutes of Health Stroke Scale (NIHSS) score > 2; and (5) informed consent was obtained from all the patients or their legal relatives.
Exclusion criteria
Exclusion criteria: (1) Hemorrhagic stroke; (2) coma; (3) obvious symptoms of defective nervous system before the onset of stroke; (4) existed self-injurious or suicidal tendency, and needed antidepressants urgently; (5) used antidepressants within 3 months before the onset or benzodiazepines within 2 weeks before the onset; (6) serious heart diseases, respiratory failure, malignant tumor; (7) active peptic ulcer or other gastrointestinal diseases, which may affect the absorption of drugs; (8) liver enzymes or creatinine were abnormal; (9) pregnant or lactating women; (10) severe mental disorders, such as schizophrenia; (11) allergic constitution; (12) participated in other clinical studies within 3 months before the study; and (13) planned to receive endovascular treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NIHSS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| BI score;Blood glucose;Blood lipids;Blood pressure;Stroke recurrence;Relative drug side effects; | — |
Countries
China
Contacts
Public ContactGuo Yi
Outcome results
None listed