Acne vulgaris
Conditions
Interventions
Experiment group :niacin and other vitamin
control group:nicotinamide
Sponsors
1st hospital, Guangxi University of Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Male and female acne patients, to be aged 10 to 40 year-old; 2. Acne patients should to agree to participate this study and signed informed consent; 3. The healthy controls should not taking any medication and had no personal or family history of severe acne. Healthy volunteers had no acne lesions, or acne scar; no psoriasis; no alopecia; no gallbladder disease, diabetes or neuroendocrine disorders; no history of hypertension, liver or kidney dysfunction, heart disease, or cancer; and they had had mild acne in adolescence (or many years ago) but were not under any treatment for acne, to avoid the effect of other endocrine disturbance. Some healthy people who might have had mild acne that had been healed for >2 years without taken any medication were also recruited in the control group.
Exclusion criteria
Exclusion criteria: 1. used oral antibiotics, topical agents, or phototherapy during the past 4 weeks of preceding the trial; 2. pregnancy or lactation; 3. patients with a history of allergies, or heart, liver, or kidney dysfunction; 4. very severe case need antibiotics treatment; 5. those who could not tolerate the side effects of niacin; 6. Patient is participating in other clinical trials; 7. researchers believe that other reasons were not suitable for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The percentage of improvement; | — |
Countries
China
Contacts
Public ContactJiang Hao
Outcome results
None listed