ovarian cancer
Conditions
Interventions
trial group:DC/CTL venous return
Sponsors
Shandong Cancer Hospitai&Institute
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: (1) Women, age from 20 to 70 years old; (2) Pathological diagnosis of stage III epithelial ovarian cancer (based on "NCCN Guidelines for Ovarian Cancer" 2013 Chinese version); (3) Child-Pugh score 3*10^9/L; Neutrophils >1.5*10^9/L; Hemoglobin>=85g/L; Platelets>=50*10^9/L; PT normal or extended time <3 seconds; Blood urea nitrogen (BUN) andserum creatinine<=1.5times the upper limit of normal; (7) Sign informed consent voluntarily.
Exclusion criteria
Exclusion criteria: (1) Receiving systemic or long-term treatments with immunomodulatory agents such as interferon, thymosin, Traditional Chinese Medicine, etc., or immunosuppressive agents such as adrenal corticosteroids (systemic or long-term application is defined that immunomodulatory agent is continuously used for more than 3 months or immunosuppressive agent is continuously used for over 1 month) within 6 months; (2) Receiving any cellular immunotherapy (including NK, CIK, DC, CTL, stem cells, etc.) within 6 months; (3) HIV or HCV antibody test positive; (4) A history of immune deficiency diseases or autoimmune diseases (such as rheumatoid arthritis, Buergers disease, multiple sclerosis andtype 1 diabetes); (5) Cancers (except skin cancer, local prostate cancer or cervical carcinoma in situ) diagnosed within 5 years; (6) Any organ failure; (7) Severe mental illness; (8) A history of drug addiction (including alcohol) within 1 year; (9) Participated in other clinical trials within 3 months; (10) Other investigators believe that the patient is not suitable for this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| recurrence;metastasis;death; | — |
Secondary
| Measure | Time frame |
|---|---|
| The quality of life; | — |
Countries
Chinese
Contacts
Public ContactSheng Xiuggui
Outcome results
None listed