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The Application of the Perioperative Parenteral Nutrition Support with Multi-oil Fat Emulsion in Elderly Patients with Gastric Cancer

The Application of the Perioperative Parenteral Nutrition Support with Multi-oil Fat Emulsion in Elderly Patients with Gastric Cancer

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-15007557
Enrollment
Unknown
Registered
2015-12-03
Start date
2013-12-28
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric Cancer

Interventions

Control group:The control group were not given nutrition support preoperative,moreover they were given parenteral nutrition support including 20% Intralipid for a week after operation.
Intralipid group:The Intralipid group were given parenteral nutrition support including 20% Intralipid for a week both preoperative and postoperation.
SMOF group:The SMOF group were given parenteral nutrition support including Multi-oil Fat Emulsion for a week both preoperative and postoperation.

Sponsors

The First Affiliated Hospital of Fujian Medical University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
65 Years to 83 Years

Inclusion criteria

Inclusion criteria: (1) elderly patients with gastric cancer who were confirmed by gastroscope pathological preoperative, according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative; (2) According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points; (3) they were with normal hepatic and renal function before surgery; (4) hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery; (5) Without radiotherapy, and chemotherapy preoperative.

Exclusion criteria

Exclusion criteria: (1) preoperative examination showed moderate anemia, hemoglobin (2.26mmol/L or total cholesterol >6.2mmol/L; (8) obese or overweight patients, body mass index > 28; (9) operation time is more than 180 minutes, intraoperative bleeding is more than 800 ml; (10) unable to radical resection, or implemented with splenectomy.

Design outcomes

Primary

MeasureTime frame
albumin;prealbumin;Serum transferrin;alanine aminotransferase;total bilirubin;T lymphocyte subsets (CD3, CD4, CD8, CD4/CD8);immunoglobulin(IgA, IgG, IgM);C-reactive protein;interleukin-6;the patients’ average length of stay;average hospitalization expenses;incidence rate of perioperative complication;

Countries

China

Contacts

Public ContactPan Dun
pandun0220@163.com+86 13860617622

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026