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One-stage debridement,bone graft and instrumentation and drainage and local chemotherapy for spina tuberculosis: A randomized controlled trial

One-stage debridement,bone graft and instrumentation and drainage and local chemotherapy for spina tuberculosis: A randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-15007556
Enrollment
Unknown
Registered
2015-12-06
Start date
2015-12-30
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spinal tuberculosis

Interventions

Control group:One-stage debridement,bone graft and instrumentation
experimental group:one-stage debridement, bone graft and instrumentation and drainage and local chemotherapy

Sponsors

Spine and Osteopathy Ward, The First Affiliated Hospital of Guangxi Medical
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Spinal tuberculosis was diagnosed according to symptoms, physical signs, imaging examination results, and etiological and histopathological results.Patients receiving initial were included; 2. no contraindications to surgery were noted; 3. Patients were evaluated and were found to be appropriate candidates for surgical focus debridement for tuberculosis.

Exclusion criteria

Exclusion criteria: 1. Spinal tubeculosis was diagnlosed unclear, or were excluded by according to etiological and histopathological results; 2. Lost to follow-up; 3. No compliant with the recommended chemotherapy treatment.

Design outcomes

Primary

MeasureTime frame
Erythrocyte sedimentation rate;C-reactive protein;X-ray;Computer Tomography;magnetic resonance imaging;correction of deformity;ASIA scores;ability to live and work;recurrence were observed;liver and kidney function;side effects of chemotherapy;Bacterial culture and identification;hospital stays;

Countries

China

Contacts

Public ContactXinli Zhan
3cstar@163.com+86 13907864389

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026