hyperlipemia, coronary artery disease
Conditions
Interventions
Control group:Nothing
Probucol group:oral probucol therapy for 1 week
Placebo group:oral placebo therapy for 1 week
Sponsors
Shandong Provincial Affiliated to Shandong University
Eligibility
Sex/Gender
All
Age
48 Years to 71 Years
Inclusion criteria
Inclusion criteria: Patients who had CAD and hyperlipidemia with age of at least 21 years old.
Exclusion criteria
Exclusion criteria: people with abnormal thyrotrophin (TSH) concentrations, abnormal hepatic functions, or abnormal renal functions; pregnant or breast feeding women; people that allergic to probucol; people in the acute and subacute phase of cardiac injury; people with severe arrhythmia; people with cardiac or unexplained syncope; people with QT interval prolongation or that take medicine prolong QT interval; people with hypokalemia or hypomagnesemia; people has enrolled or will be enrolled in other trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EPCs population in peripheral blood;ox-LDL;fasting lipid profile;fasting blood glucose;superoxide dismutase;C reactive protein; | — |
Secondary
| Measure | Time frame |
|---|---|
| WBC in peripheral blood; | — |
Countries
China
Contacts
Public ContactYuqi Cui
Outcome results
None listed