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Effect of Vitamin C pretreatment on propofol injection pain

Effect of Vitamin C pretreatment on propofol injection pain

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-15007456
Enrollment
Unknown
Registered
2015-11-15
Start date
2015-12-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Propofol injection pain

Interventions

Group A:2 hours preoperative intravenous vitamin C 1g
Group B:Using the same placebo as the A group.
Group C:Using the same placebo as the A group,and the injection of propofol combined with lidocaine 40mg

Sponsors

Huizhou First Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Patients who are between 18-65 years old are performed laparoscopic myomectomy under endotracheal anesthesia; 2. ASA I-II; 3. Patients participate voluntarily and sign a consent; 4. Analgesic is not used before surgery.

Exclusion criteria

Exclusion criteria: (1) serious disease of heart, lung, liver, NYHA >=III level; (2) sick sinus syndrome, bradycardia (HR < 55 times/min), degree II atrioventricular block; (3) history of heart failure, high blood pressure; (4) communication difficulty; (5) The patients have lower pain threshold than normal.

Design outcomes

Primary

MeasureTime frame
the score of VRS;

Countries

China

Contacts

Public ContactHaocong Ji
jihaocong@163.com+86 13824266224

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026