Rheumatoid arthritis
Conditions
Interventions
treatment group:sinomenine hydrochloride combined with MTX
controlled group:LEF combined with MTX
Sponsors
Guangdong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The patient must meet 1987 American College of Rheumatology classification criteria for the diagnosis of active rheumatoid arthritis and/or 2010 American College of Rheumatology /The European League Against Rheumatism classification criteria for the diagnosis of active rheumatoid arthritis; The patients must meet Class I-III of the Xray development in RA; 2. Patient has signed the informed consent; 3. Patient must be between 18 and 65 years of age.
Exclusion criteria
Exclusion criteria: 1. Infection, pregnancy, lactating, traumatic or other stress state; 2. Severe, progressive or uncontrolled cardiac, hepatic, renal, mental disease; 3. Severe hematologic disease including leukemia, aplastic anemia, myelodysplastic syndrome and so on; 4. Be allergic to the medicine we use in the research; 5. Use antibiotics within 1 month; 6. Patients in the Class? of RA; 7. History of other rheumatic autoimmune disease; 8. Patients with active gastrointestinal disease or pitents with peptic ulcer 4 or less weekly; 9. Patients who have previously participated in any clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| DAS28; | — |
Countries
China
Contacts
Public ContactQing-chun Huang
Outcome results
None listed