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The rest-fMRI and DTI possible mechanisms of repetitive transcranial magnetic stimulation on sub-acute cerebral infarct global aphasia

The rest-fMRI and DTI possible mechanisms of repetitive transcranial magnetic stimulation on sub-acute cerebral infarct global aphasia

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-IPR-15007382
Enrollment
Unknown
Registered
2015-11-09
Start date
2016-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

rTMS-STG:low frequency rTMS-STG+speech treatment
rTMS-PTr:low frequency rTMS-PTr+speech treatment
sham group:sham stimulation+speech treatment

Sponsors

Nanjing Medical University affiliated Wuxi Tongren (International) Rehabilitaion Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. ischemic infarct within the left middle cerebral artery territory by CT or MRI confirmed; 2. first-time stroke, 1 to months after stroke onset; 3. global aphasia assessed with the Western Aphasia Battery (WAB); 4. aged between 40 and 75 years old; 5. native Chinese speaker; 6. above primary school education; 7. premorbidly right-handed; 8. normal language function before stroke; 9. each subject signed a consent before participation in this study.

Exclusion criteria

Exclusion criteria: 1. visual, auditory disorders affecting the language evaluation and treatment; 2. severe cognitive dysfunction, not with the inspection and rehabilitation training; 3. previous language disorders or complicated with severe dysarthria; 4. degenerative diseases of the nervous system such as dementia, Parkinson's disease, motor neuron disease, result to speech disorder; 5. epilepsy, and drug abuse or mental disease; 6. body with metal foreign bodies or other implanted electronic devices.

Design outcomes

Primary

MeasureTime frame
The Western Aphasia Battery;The Token Test;Boston Naming Test;

Secondary

MeasureTime frame
functional and structional connection;

Countries

China

Contacts

Public ContactCaili Ren
sally7226@163.com+86 15306175051

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026