gastrointestinal cancer
Conditions
Interventions
Experiment group:Ensure
Control group:conventional diet
Sponsors
ZhangChangHua
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Men or women patients aged 18~80 years; 2. Patients who have undergone surgical resection of gastrointestinal cancers 3 or 4 weeks ago, and the expectation of life is more than 6 months; 3. Post-operative pathologic pTNM staging: stage II or III gastric cancer or colorectal cancer (NCCN version 7); 4. Patients who will receive post-operative adjuvant chemotherapy; 5. Patients with malnutrition (BMI5 6. ECOG performance status (PS) score: 0-2; 7. Blood white cell count at 3500-12000/ul; neutrophil count at 2000/ul or above; hemoglobin at 9.0 g/dL or above, platelet at 100000/ul or above; total bilirubin, aspartate amino transferase (AST) and alanine amino transferase
Exclusion criteria
Exclusion criteria: 1. Participated other clinical trials within two months prior to the study; 2. Mental disorders and poor cooperation; 3. Patients who are unable to take oral diet; 4. Intestinal bleeding, serious malabsorption, serious short bowel syndrome or fistula with high excretion amount, and serious nausea and vomiting; 5. Patients who have combined serious cardiac diseases, diabetes mellitus, hyperlipemia, electrolyte disturbances, abnormal hepatic and renal functions, or patients who are considered not suitable for participating the study; 6. Patients who received parenteral and enteral nutrition within two weeks prior to screening; 7. Pregnancy or breastfeeding or plan to be pregnant within one year; 8. Not suitable for participating the study in the investigators opinion; 9. Patients who are allergic to milk or soybean protein; 10. Patients who may use other nutritional products during the study, such as protein powder, bovine colostrum etc. 11. Patients who are not willing to provide their informed consent form (ICF) or by their authorized representative;
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Nutritional indicators;Immunity indicators;Incidence of adverse reactions of chemotherapy;Quality of life score;Blood test; | — |
Primary
| Measure | Time frame |
|---|---|
| PG-SGA score; | — |
Countries
China
Contacts
Public ContactZhang Changhua
Outcome results
None listed